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KMID : 0352419920110020307
Keimyung Medical Journal
1992 Volume.11 No. 2 p.307 ~ p.314
A Clinical Study of Primary Gallbladder Cancer in 75 surgical Patients


Abstract
The results of retrospective study is represented in 75 gallbladder cancer patients who underwent surgical procedures at surgical department of Dong-San Medical Center, Keimyung University from January, 1976 to December 1991.
Primary carcinoma of the gallbladder was seen most commonly in the age group of fifties and sixties and this group occupied 74.6% entire group. Of a total 75 patients 52 were female, 23 were male and the female to male ratio was 2.3 : 1.
Upper abdominal pain (80%) was the most common clinical symptom followed by anorexia, weight loss. Right upper quadrant abdominal tenderness was the most frequent physical finding (53.3%) followed by palpable mass and jaundice.
Cholecystitis was the most common preoperative diagnosis (44%) and the corret diagnosis of the carcinoma of the gallbladder was made in 24% of the cases.
Operative procedures performed include: Cholecystectomy alone(38.7%), Cholecystectomy with T-tube insertion (30.7%), cholecystectomy with excision of the gallbladder bed and cholecystectomy with choledochoenterostomy.
The most common site of metastasis was the liver (41.3%), followed by porta hepatis (24%) and regional lymph node.
The most frequent associated disease was cholecystitis (24%), followed by gallstone (22.7%) and empyema of the gallbladder.
The most common histological type was adenocarcinoma (83.6%), followed by anaplastic type, squamous carcinoma and adenosquamous carcinoma.
Postoperative complications include wound infection, hepatorenal syndrome, septicemia and bile peritonitis.
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